Aug 272018
 

Arvind talks about new research findings and tools to assess risk and tackle Coronary Heart Disease.

Everyone is aware of rising incidence of cardiovascular disease and more particularly Coronary Heart Disease (CHD) due to Atherosclerosis. What is sad is that most of these cases are preventable, controllable or even perhaps reversible if TRUE risk factors were assessed early and corrective action taken at an early stage.

Recent research in this field has given us new insights and important tools to assess the risk more accurately. Unfortunately most people may still be focussing on Cholesterol/LDLC (Low-Density Lipoprotein Cholesterol) as sole target for intervention. Growing body of research suggests that, although LDLC is one of the causative factors, LDLC by itself may not be an accurate risk factor. It is now being realised that a subclass called small dense LDLC and LDLP (LDL Particle Number) ARE far better risk indicators. And there is no correlation between LDLC and LDLP or sdLDL (small dense low density lipoprotein). Research is also showing that risk markers such as Tri Glycerides and Insulin levels have more bearing on the risk for CHD. In that case we may be barking up the wrong tree and concentrating only on reducing LDLC.

We would understand how high insulin levels affect Atherosclerosis process. This is the reason why people with Diabetes type II have such high incidence of CHD. In fact high insulin levels due to insulin resistance is the basic root cause for all the diseases of the cluster known as Metabolic Syndrome.

Finally we would take a look at what actions we can take in terms of lifestyle changes and medicines to prevent, stabilize and even reverse the disease. You may be surprised to find that to overcome diseases connected with metabolic syndrome like Obesity, Diabetes Type II and also excessive TG / sdLDL levels connected with CHD, the diet solution is identical and that is to replace carbs with fat.

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